Anaphylactic shock is the most severe, life-threatening stage of a generalized allergic reaction (anaphylaxis). It happens when your immune system overreacts to a trigger—such as a food, medication, or insect sting—and releases a flood of chemicals like histamine.1234
What Happens in the Body
- Dangerous drop in blood pressure: Blood vessels widen rapidly, causing circulation to fail and cutting off oxygen to vital organs.
- Airway constriction: Bronchial tissues swell and narrow, making it difficult or impossible to breathe.
- Multi-system involvement: Symptoms often affect the skin (hives, flushing), respiratory tract (wheezing, stridor), and heart (rapid pulse or cardiac arrest) simultaneously.123456
Common Triggers
- Foods: Peanuts, tree nuts, milk, eggs, fish, shellfish, and sesame.
- Insect stings: Bees, wasps, and hornets.
- Medications: Antibiotics (like penicillin) or pain relievers.
- Other agents: Natural rubber latex.1234567
Immediate Action & Treatment
Anaphylactic shock is a medical emergency that requires instant intervention:12
- Use adrenaline (epinephrine): Administer an adrenaline auto-injector (such as an EpiPen) immediately.
- Call emergency services: Contact emergency services right away.
- Position the person: Lie them down and raise their legs (unless they are struggling to breathe, in which case they can sit up or elevate their shoulders; pregnant individuals should lie on their left side).
- Seek hospital care: Professional emergency treatment with intravenous fluids, oxygen, and repeat doses of medication is necessary, as symptoms can sometimes return in a second wave (biphasic reaction).123456
You can learn more about emergency protocols from the NHS Anaphylaxis Guide or the Cleveland Clinic Anaphylaxis Overview.12If you'd like, let me know:
- Are you asking for general information, or do you or someone nearby have specific symptoms right now?
- Do you need to know how to use an adrenaline auto-injector?
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